Protein inhibitor points to potential medical treatments for skull and skin...
Researchers at Mount Sinai School of Medicine in New York have found new clues in the pathogenesis of skull and skin birth defects associated with a rare genetic disorder, Beare-Stevenson cutis gyrata...
View ArticleResearchers solve mystery surrounding the death of two sisters nearly 50...
Researchers at Mount Sinai School of Medicine have identified the genetic cause of a rare and fatal bone disease by studying frozen skin cells that were taken from a child with the condition almost...
View ArticleTen years on, still much to be learned from human genome map
(HealthDay)—As scientists mark the 10th anniversary Sunday of the completion of the Human Genome Project, they will note how that watershed effort has led to the discovery of the genetic underpinnings...
View ArticleResearchers identify first drug targets in childhood genetic tumor disorder
Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets,...
View ArticleGenetic editing shows promise in Duchenne muscular dystrophy
Using a novel genetic 'editing' technique, Duke University biomedical engineers have been able to repair a defect responsible for one of the most common inherited disorders, Duchenne muscular...
View ArticleGut bacteria play key role in vaccination, study finds
The bacteria that live in the human gut may play an important role in immune response to vaccines and infection by wild-type enteric organisms, according to two recent studies resulting from a...
View ArticleBacterial DNA may integrate into human genome more readily in tumor tissue
Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, according to a new study from the University of Maryland School of Medicine's Institute for Genome...
View ArticleHigher genetic risk tied to lifetime asthma suffering
Children with more genetic risks for asthma are not only more likely to develop the condition at a young age, but they are also more likely to continue to suffer with asthma into adulthood. The finding...
View ArticleBiomarker predicts heart attack risk based on response to aspirin therapy
Aspirin has been widely used for more than 50 years as a common, inexpensive blood thinner for patients with heart disease and stroke, but doctors have little understanding of how it works and why some...
View ArticleResearch shows gut microbe populations stable over years, probably decades
(Medical Xpress)—The importance of the bacteria that live within our digestive tracts is just beginning to be fully realized, and while it has long been known that they assist in digestion and...
View ArticleResearchers find that proteins involved in immunity potentially cause cancer
A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. The findings...
View ArticleResearchers explore new treatments for a leading genetic cause of infant deaths
Researchers at Iowa State University have identified an RNA structure in humans that could lead to a new treatment for spinal muscular atrophy, the leading genetic cause of death in babies and young...
View ArticleStudy identifies therapy that may curb kidney deterioration in patients with...
A team led by researchers at the National Institutes of Health has overcome a major biological hurdle in an effort to find improved treatments for patients with a rare disease called methylmalonic...
View ArticleHuman cells respond in healthy, unhealthy ways to different kinds of happiness
Human bodies recognize at the molecular level that not all happiness is created equal, responding in ways that can help or hinder physical health, according to new research led by Barbara L....
View ArticleResearchers publish study on genome of aggressive cervical cancer that killed...
A team from the University of Washington has unveiled a comprehensive portrait of the genome of the world's first immortal cell line, known as HeLa. The cell line was derived in 1951 from an aggressive...
View ArticleNew characterization of human genome mutability catalyzes biomedical research
As biomedical researchers continue to make progress toward the realization of personalized genomic medicine, their focus is increasingly tuned to highly mutable regions of the human genome that...
View ArticleWhole DNA sequencing reveals mutations, new gene for blinding disease
Retinitis pigmentosa (RP) is a genetic disease that causes progressive loss of vision and is caused by mutations in more than 50 genes. Conventional methods for identification of both RP mutations and...
View ArticleScientists characterize effects of transplanted fecal microbiota
Scientists at the Institute for Genome Sciences at the University of Maryland School of Medicine and physicians at Sinai Hospital, Baltimore, MD, have found that restoring the normal, helpful bacteria...
View ArticleDawn of the genome era
The Human Genome Project concluded in 2003, but many of its benefits are only now being realized, according to Alan Guttmacher, director of the National Institutes of Health's Eunice Kennedy Shriver...
View ArticleNew understanding of chlamydial disease: Novel simultaneous RNA-Seq analysis...
Investigators at the Institute for Genome Sciences at the University of Maryland School of Medicine have developed a new technique that can track the activity of a disease-causing microbe and the host...
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