Researchers explore new treatments for a leading genetic cause of infant deaths
Researchers at Iowa State University have identified an RNA structure in humans that could lead to a new treatment for spinal muscular atrophy, the leading genetic cause of death in babies and young...
View ArticleStudy identifies therapy that may curb kidney deterioration in patients with...
A team led by researchers at the National Institutes of Health has overcome a major biological hurdle in an effort to find improved treatments for patients with a rare disease called methylmalonic...
View ArticleHuman cells respond in healthy, unhealthy ways to different kinds of happiness
Human bodies recognize at the molecular level that not all happiness is created equal, responding in ways that can help or hinder physical health, according to new research led by Barbara L....
View ArticleResearchers publish study on genome of aggressive cervical cancer that killed...
A team from the University of Washington has unveiled a comprehensive portrait of the genome of the world's first immortal cell line, known as HeLa. The cell line was derived in 1951 from an aggressive...
View ArticleNew characterization of human genome mutability catalyzes biomedical research
As biomedical researchers continue to make progress toward the realization of personalized genomic medicine, their focus is increasingly tuned to highly mutable regions of the human genome that...
View ArticleWhole DNA sequencing reveals mutations, new gene for blinding disease
Retinitis pigmentosa (RP) is a genetic disease that causes progressive loss of vision and is caused by mutations in more than 50 genes. Conventional methods for identification of both RP mutations and...
View ArticleScientists characterize effects of transplanted fecal microbiota
Scientists at the Institute for Genome Sciences at the University of Maryland School of Medicine and physicians at Sinai Hospital, Baltimore, MD, have found that restoring the normal, helpful bacteria...
View ArticleDawn of the genome era
The Human Genome Project concluded in 2003, but many of its benefits are only now being realized, according to Alan Guttmacher, director of the National Institutes of Health's Eunice Kennedy Shriver...
View ArticleNew understanding of chlamydial disease: Novel simultaneous RNA-Seq analysis...
Investigators at the Institute for Genome Sciences at the University of Maryland School of Medicine have developed a new technique that can track the activity of a disease-causing microbe and the host...
View ArticleGut bacteria shift quickly after changes in diet, study shows
(HealthDay)—If you were to switch from vegetarianism to meat-eating, or vice-versa, chances are the composition of your gut bacteria would also undergo a big change, a new study suggests.
View ArticleCommon disorders: It's not the genes themselves, but how they are controlled
Many rare disorders are caused by gene mutation, like sickle cell anemia. Yet until now the underlying genetic cause of more common conditions – for example, rheumatoid arthritis – has evaded...
View ArticleAcademics decry FDA crackdown on genome service companies
(Medical Xpress)—Dr. Robert Green, a medical geneticist with Brigham and Women's Hospital and Nita Farahany, professor of genome sciences and policy at Duke University, who also happens to be a lawyer...
View ArticleNew forms of racism arise in science research
Advances in genetic sequencing are giving rise to a new era of scientific racism, despite decades of efforts to reverse attitudes used to justify the slave trade and Nazi theology, experts said on Friday.
View ArticleThousands of never-before-seen human genome variations uncovered
Thousands of never-before-seen genetic variants in the human genome have been uncovered using a new genome sequencing technology. These discoveries close many human genome mapping gaps that have long...
View ArticleNew study validates usefulness of genomic medicine in children with...
Results from more than 100 families with children affected by a broad range of neurologic and developmental disorders who underwent genomic testing to end their quest for a diagnosis, were published...
View ArticleEbola virus has mutated less than scientists feared, study finds
The Ebola virus is not mutating as quickly as scientists had feared, which is good news for treating the disease and preventing its spread, a study showed Thursday.
View ArticleSome false postive prenatal genetic screens due to mother's extra DNA segments
Prenatal blood screening for extra or missing chromosomes in the fetus might give false-positive results if the mother's genome contains more than the usual number of certain DNA segments. This finding...
View ArticleStudy reveals possible new avenues for breast cancer therapy
An exhaustive analysis has been conducted of more than 12,000 distinct proteins present in an often aggressive and difficult to treat form of breast cancer, called triple-negative breast cancer.
View ArticleFamily genetics study reveals new clues to autism risk
A study of 2,377 children with autism, their parents and siblings has revealed novel insights into the genetics of the condition.
View ArticleDigital 'Rosetta Stone' decrypts how mutations rewire cancer cells
Scientists have discovered how genetic cancer mutations systematically attack the networks controlling human cells, knowledge critical for the future development of personalized precision cancer...
View ArticleDormant viral genes may awaken to cause ALS
Scientists at the National Institutes of Health discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic...
View ArticlePowerful genetic regulator identified as risk factor for schizophrenia
By turning skin cells into brain neurons, researchers at the Icahn School of Medicine at Mount Sinai have identified that certain tiny molecules aiding in gene expression, known as microRNAs (miRNAs),...
View ArticleScientists propose project that includes making human DNA (Update)
Scientists proposed a long-term project Thursday that involves creating DNA blueprints for making human beings, a prospect some observers find troubling.
View ArticleSingle gene mutation causes severely debilitating disease of brain blood vessels
The cause of a disease that targets blood vessels in the brain - leading to multiple debilitating symptoms and, often, to early death - has been tracked to a single mutated gene, opening up the...
View ArticleResearchers unveil new wound-healing role for protein-folding gene in mice
National Institutes of Health researchers have identified a novel role for a gene known as heat shock protein 60 (Hsp60), finding that it is critical in tissue regeneration and wound healing. The study...
View ArticleMolecular structure in Zika virus leads to potentially disease-causing RNAs
Researchers, led by scientists at the University of Colorado School of Medicine, have found basic molecular processes used by the Zika virus to "hijack" the cells that it infects and potentially how it...
View ArticleStudy leads to breakthrough in better understanding acute myeloid leukemia
A study led by the University of Birmingham has made a breakthrough in the understanding of how different genetic mutations cause acute myeloid leukaemia.
View ArticleCan genetics play a role in education and well-being?
When Daniel Benjamin was just beginning his PhD program in economics in 2001, he attended a conference with his graduate school advisers. They took in a presentation on neuroeconomics, a nascent field...
View ArticleSequencing all 24 human chromosomes uncovers rare disorders
Extending noninvasive prenatal screening to all 24 human chromosomes can detect genetic disorders that may explain miscarriage and abnormalities during pregnancy, according to a study by researchers at...
View ArticleExperts argue for payors to make better use of genomic testing for cancer...
(Medical Xpress)—Harold Varmus, former National Cancer Institute Director and Rebecca Eisenberg a professor at the University of Michigan Law School have published a Policy Forum paper in the journal...
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